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Document type:
journal article 
Author(s):
Mazur, PK; Riener, MO; Jochum, W; Kristiansen, G; Weber, A; Schmid, RM; Siveke, JT 
Title:
Expression and clinicopathological significance of notch signaling and cell-fate genes in biliary tract cancer. 
Abstract:
Biliary tract cancer (BTC) is a fatal cancer originating from epithelial cells of the intra- and extra-hepatic biliary duct system and the gallbladder. Genes and pathways regulating stem and progenitor cells as well as cell-fate decisions are increasingly recognized in tumorigenesis. We evaluated the expression of Notch1, Notch2, and HES1 (hairy and enhancer of split 1), as well as the biliary cell-fate regulators SOX9 (SRY (sex determining region Y)-box 9) and HNF1? (hepatocyte nuclear factor 1...    »
 
Journal title abbreviation:
Am J Gastroenterol 
Year:
2012 
Journal volume:
107 
Journal issue:
Pages contribution:
126-35 
Language:
eng 
Print-ISSN:
0002-9270 
TUM Institution:
II. Medizinische Klinik und Poliklinik