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Document type:
journal article 
Author(s):
Christensen, JE; Fenger, C; Issazadeh-Navikas, S; Krug, A; Liljestrøm, P; Goriely, S; Paludan, SR; Finsen, B; Christensen, JP; Thomsen, AR 
Title:
Differential impact of interferon regulatory factor 7 in initiation of the type I interferon response in the lymphocytic choriomeningitis virus-infected central nervous system versus the periphery. 
Abstract:
Interferon (IFN) regulatory factors (IRFs) are a family of transcription factors involved in regulating type I IFN genes and other genes participating in the early antiviral host response. To better understand the mechanisms involved in virus-induced central nervous system (CNS) inflammation, we studied the influence of IRF1, -3, -7, and -9 on the transcriptional activity of key genes encoding antiviral host factors in the CNS of mice infected with lymphocytic choriomeningitis virus (LCMV). A ke...    »
 
Journal title abbreviation:
J Virol 
Year:
2012 
Journal volume:
86 
Journal issue:
13 
Pages contribution:
7384-92 
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
II. Medizinische Klinik und Poliklinik