Total Synthesis of Polyrhacitides A and B by Use of an Iterative Strategy for the Stereoselective Synthesis of 1,3-Polyol Arrays
The first total syntheses of polyrhacitides A and B, secondary metabolites from Chinese medicinal ants, were accomplished via an iterative approach to the 1,3-polyol motif. For the construction of all stereogenic centers, the catalytic asymmetric Overman esterification was utilized.
ISI Document Delivery No.: 528QO Times Cited: 19 Cited Reference Count: 84 Menz, Helge Kirsch, Stefan F. Fonds der Chemischen Industrie (FCI) This project was supported by the Fonds der Chemischen Industrie (FCI). The authors thank Prof. Dr. Th. Bach (TUM) for helpful ideas and great support and O. Ackermarm (TUM) for determining the enantiopurity of 5 19 Amer chemical soc Washington