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Document type:
journal article 
Author(s):
Bussmann, C; Weidinger, S; Novak, N 
Title:
Genetics of atopic dermatitis. 
Abstract:
Atopic dermatitis (AD) is a multifactorial disease, with a strong genetic predisposition. Genome-wide studies as well as candidate gene studies revealed several susceptibility loci. Since the observation of a strong association of "loss of function" mutations in the filaggrin gene with AD, the epidermal barrier was rediscovered as important pathophysiological co-factor of this disease. 
Journal title abbreviation:
J Dtsch Dermatol Ges 
Year:
2011 
Journal volume:
Journal issue:
Pages contribution:
670-6 
Language:
eng 
Print-ISSN:
1610-0379 
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie