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Document type:
journal article 
Author(s):
Yasuno, K; Bilguvar, K; Bijlenga, P; Low, SK; Krischek, B; Auburger, G; Simon, M; Krex, D; Arlier, Z; Nayak, N; Ruigrok, YM; Niemelä, M; Tajima, A; von und zu Fraunberg, M; Dóczi, T; Wirjatijasa, F; Hata, A; Blasco, J; Oszvald, A; Kasuya, H; Zilani, G; Schoch, B; Singh, P; Stüer, C; Risselada, R; Beck, J; Sola, T; Ricciardi, F; Aromaa, A; Illig, T; Schreiber, S; van Duijn, CM; van den Berg, LH; Perret, C; Proust, C; Roder, C; Ozturk, AK; Gaál, E; Berg, D; Geisen, C; Friedrich, CM; Summers, P; Fr...    »
 
Title:
Genome-wide association study of intracranial aneurysm identifies three new risk loci. 
Abstract:
Saccular intracranial aneurysms are balloon-like dilations of the intracranial arterial wall; their hemorrhage commonly results in severe neurologic impairment and death. We report a second genome-wide association study with discovery and replication cohorts from Europe and Japan comprising 5,891 cases and 14,181 controls with approximately 832,000 genotyped and imputed SNPs across discovery cohorts. We identified three new loci showing strong evidence for association with intracranial aneurysm...    »
 
Journal title abbreviation:
Nat Genet 
Year:
2010 
Journal volume:
42 
Journal issue:
Pages contribution:
420-5 
Language:
eng 
Print-ISSN:
1061-4036 
TUM Institution:
Neurochirurgische Klinik und Poliklinik