User: Guest  Login
Document type:
journal article 
Author(s):
Fernández-Klett, F; Offenhauser, N; Dirnagl, U; Priller, J; Lindauer, U 
Title:
Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. 
Abstract:
Modern functional imaging techniques of the brain measure local hemodynamic responses evoked by neuronal activity. Capillary pericytes recently were suggested to mediate neurovascular coupling in brain slices, but their role in vivo remains unexplored. We used two-photon microscopy to study in real time pericytes and the dynamic changes of capillary diameter and blood flow in the cortex of anesthetized mice, as well as in brain slices. The thromboxane A(2) analog, 9,11-dideoxy-9?,11?-methanoepox...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2010 
Journal volume:
107 
Journal issue:
51 
Pages contribution:
22290-5 
Language:
eng 
Print-ISSN:
0027-8424 
TUM Institution:
Neurochirurgische Klinik und Poliklinik