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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Szczuraszek, K; Halon, A; Materna, V; Mazur, G; Wrobel, T; Kuliczkowski, K; Donizy, P; Holm, PS; Lage, H; Surowiak, P 
Title:
Elevated YB-1 expression is a new unfavorable prognostic factor in non-Hodgkin's lymphomas. 
Abstract:
Y-Box-binding protein-1 (YB-1) acts as a transcription factor for multiple genes and is linked to DNA replication and repair, cell proliferation and resistance to cytostatic drugs.The prognostic value of YB-1 expression in primarily untreated malignant non-Hodgkin's lymphomas (NHLs) was examined using immunohistochemistry.Expression of YB-1 was detected in 48 out of 56 NHLs, and the immunohistochemical reaction was localized exclusively in the cytoplasm. Expression of YB-1 did not correlate with...    »
 
Journal title abbreviation:
Anticancer Res 
Year:
2011 
Journal volume:
31 
Journal issue:
Pages contribution:
2963-70 
Language:
eng 
Print-ISSN:
0250-7005 
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung