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Document type:
Zeitschriftenaufsatz 
Author(s):
Lee, Chien-Yun; Wang, Dongxue; Wilhelm, Mathias; Zolg, Daniel P.; Schmidt, Tobias; Schnatbaum, Karsten; Reimer, Ulf; Pontén, Fredrik; Uhlén, Mathias; Hahne, Hannes; Kuster, Bernhard 
Title:
Mining the Human Tissue Proteome for Protein Citrullination 
Abstract:
Citrullination is a post-translational modification of arginine catalyzed by five peptidylarginine deiminases (PADs) in humans. The loss of a positive charge may cause structural or functional alterations and while the modification has been linked to several diseases including rheumatoid arthritis and cancer, its physiological or pathophysiological roles remain largely unclear. In part this is owing to limitations in available methodology able to robustly enrich, detect and localize the modifica...    »
 
Journal title:
Molecular & Cellular Proteomics 
Year:
2018 
Journal volume:
17 
Journal issue:
Pages contribution:
1378-1391 
Publisher:
Elsevier BV 
E-ISSN:
1535-9476 
Date of publication:
01.07.2018