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- Document type:
- Zeitschriftenaufsatz
- Author(s):
- Aleksieva, G., Hollweck, T., Thierfelder, N., Haas, U., Koenig, F., Fano, C., Dauner, M., Wintermantel, E., Reichart, B., Schmitz, C., Akra, B.
- Title:
- Use of a special bioreactor for the cultivation of a new flexible polyurethane scaffold for aortic valve tissue engineering
- Abstract:
- BACKGROUND: Tissue engineering represents a promising new method for treating heart valve diseases. The aim of this study was evaluate the importance of conditioning procedures of tissue engineered polyurethane heart valve prostheses by the comparison of static and dynamic cultivation methods. METHODS: Human vascular endothelial cells (ECs) and fibroblasts (FBs) were obtained from saphenous vein segments. Polyurethane scaffolds (
- Keywords:
- Aortic Valve/*cytology *Bioreactors Extracellular Matrix/drug effects/metabolism Fibroblasts/cytology/drug effects Gene Expression Regulation/drug effects Heart Valve Prosthesis Human Umbilical Vein Endothelial Cells/cytology/drug effects Humans Polyurethanes/*pharmacology Tissue Engineering/*methods *Tissue Scaffolds
- Congress title:
- Aleksieva, Genoveva Hollweck, Trixi Thierfelder, Nikolaus Haas, Ulrike Koenig, Fabian Fano, Cornelia Dauner, Martin Wintermantel, Erich Reichart, Bruno Schmitz, Christoph Akra, Bassil eng Research Support, Non-U.S. Gov't England 2012/12/05 06:00 Biomed Eng Online. 2012 Dec 4; 11:92. doi: 10.1186/1475-925X-11-92.
- Journal title:
- Biomed Eng Online
- Year:
- 2012
- Journal volume:
- 11
- Pages contribution:
- 92
- Covered by:
- Web of Science
- Reviewed:
- ja
- Fulltext / DOI:
- doi:10.1186/1475-925X-11-92
- Format:
- Text
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