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Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Andersen, CA; Rosenkrands, I; Olsen, AW; Nordly, P; Christensen, D; Lang, R; Kirschning, C; Gomes, JM; Bhowruth, V; Minnikin, DE; Besra, GS; Follmann, F; Andersen, P; Agger, EM
Title:
Novel generation mycobacterial adjuvant based on liposome-encapsulated monomycoloyl glycerol from Mycobacterium bovis bacillus Calmette-Guérin.
Abstract:
The immunostimulatory activity of lipids associated with the mycobacterial cell wall has been recognized for several decades and exploited in a large variety of different adjuvant preparations. Previously, we have shown that a mycobacterial lipid extract from Mycobacterium bovis bacillus Calmette-Guérin delivered in cationic liposomes was a particular efficient Th1-inducing adjuvant formulation effective against tuberculosis. Herein, we have dissected the adjuvant activity of the bacillus Calmet...    »
Journal title abbreviation:
J Immunol
Year:
2009
Journal volume:
183
Journal issue:
4
Pages contribution:
2294-302
Language:
eng
Print-ISSN:
0022-1767
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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