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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article
Author(s):
Schulz, C; Konrad, I; Sauer, S; Orschiedt, L; Koellnberger, M; Lorenz, R; Walter, U; Massberg, S
Title:
Effect of chronic treatment with acetylsalicylic acid and clopidogrel on atheroprogression and atherothrombosis in ApoE-deficient mice in vivo.
Abstract:
Acetylsalicylic acid (ASA) and the thienopyridine clopidogrel are established anti-platelet drugs that significantly reduce secondary cardiovascular events in patients with manifest atherosclerosis. However, their impact on atherosclerotic lesion development remains controversial. Four-week-old ApoE-deficient mice were randomly assigned to four groups receiving a cholesterol diet together with either ASA (5 mg/kg), or clopidogrel (25 mg/kg), or a combination of both ASA and clopidogrel, or vehic...     »
Journal title abbreviation:
Thromb Haemost
Year:
2008
Journal volume:
99
Journal issue:
1
Pages contribution:
190-5
Language:
eng
Fulltext / DOI:
doi:10.1160/TH07-03-0235
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18217153
Print-ISSN:
0340-6245
TUM Institution:
I. Medizinische Klinik und Poliklinik (Kardiologie)
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