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Document type:
journal article 
Author(s):
Deutsch, Marcus-André; Doppler, Stefanie A; Li, Xinghai; Lahm, Harald; Santamaria, Gianluca; Cuda, Giovanni; Eichhorn, Stefan; Ratschiller, Thomas; Dzilic, Elda; Dreßen, Martina; Eckart, Annekathrin; Stark, Konstantin; Massberg, Steffen; Bartels, Anna; Rischpler, Christoph; Gilsbach, Ralf; Hein, Lutz; Fleischmann, Bernd K; Wu, Sean M; Lange, Rüdiger; Krane, Markus 
Title:
Reactivation of the Nkx2.5 cardiac enhancer after myocardial infarction does not presage myogenesis. 
Abstract:
The contribution of resident stem or progenitor cells to cardiomyocyte renewal after injury in adult mammalian hearts remains a matter of considerable debate. We evaluated a cell population in the adult mouse heart induced by myocardial infarction (MI) and characterized by an activated Nkx2.5 enhancer element that is specific for multipotent cardiac progenitor cells (CPCs) during embryonic development. We hypothesized that these MI-induced cells (MICs) harbour cardiomyogenic properties similar t...    »
 
Journal title abbreviation:
Cardiovasc Res 
Year:
2018 
Journal volume:
114 
Journal issue:
Pages contribution:
1098-1114 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0008-6363 
TUM Institution:
Klinik für Herz- und Gefäßchirurgie