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Document type:
journal article 
Author(s):
Varasteh, Zohreh; Mohanta, Sarajo; Li, Yuanfang; López Armbruster, Nicolás; Braeuer, Miriam; Nekolla, Stephan G; Habenicht, Andreas; Sager, Hendrik B; Raes, Geert; Weber, Wolfgang; Hernot, Sophie; Schwaiger, Markus 
Title:
Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques. 
Abstract:
Rupture-prone atherosclerotic plaques are characterized by heavy macrophage infiltration, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR, CD206) is over-expressed in several types of alternatively activated macrophages. In this study, our objective was to evaluate the feasibility of a Gallium-68 (Ga)-labelled anti-MR nanobody (Ga-anti-MMR Nb) for the visualization of MR-positive (MR) macrophages in atherosclerotic plaques of apol...    »
 
Journal title abbreviation:
EJNMMI Res 
Year:
2019 
Journal volume:
Journal issue:
Pages contribution:
Language:
eng 
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin