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Document type:
journal article 
Author(s):
John, Harald; Siegert, Markus; Eyer, Florian; Worek, Franz; Thiermann, Horst; Kranawetvogl, Andreas 
Title:
Novel cysteine- and albumin-adduct biomarkers to prove human poisoning with the pesticide oxydemeton-S-methyl. 
Abstract:
We herein report on the forensic analysis of plasma samples to prove human poisoning with oxydemeton-S-methyl (ODM), S-(2-(ethylsulfinyl)ethyl)-O,O-dimethyl phosphorothioate. This organophosphorus pesticide is the active ingredient of Metasystox, that was swallowed by a 77-year-old woman to commit suicide. ODM belongs to the class of dimethyl phosphoryl (DMP) pesticides, contains a 2-(ethylsulfinyl)ethanethiol (ESOET) leaving group and undergoes adduct formation with endogenous molecules as elab...    »
 
Journal title abbreviation:
Toxicol Lett 
Year:
2018 
Journal volume:
294 
Pages contribution:
122-134 
Language:
eng 
Print-ISSN:
0378-4274 
TUM Institution:
Abteilung für Klinische Toxikologie