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Title:

An autoreactive T cell's perception of a land of plenty.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Comment
Author(s):
Korn, Thomas
Abstract:
Understanding the nature of human autoantigen-specific CD4+ T cells is limited by the difficulty of characterizing these cells ex vivo. In this issue of Immunity, Saggau et al. use ARTE technology to profile CD4+ T cells specific to disease-relevant autoantigens and find that such cells develop an exhausted phenotype that includes FOXP3 expression and persist for extended periods of time.
Journal title abbreviation:
Immunity
Year:
2024
Journal volume:
57
Journal issue:
10
Pages contribution:
2258-2260
Fulltext / DOI:
doi:10.1016/j.immuni.2024.09.005
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/39383840
Print-ISSN:
1074-7613
TUM Institution:
Molekulare Immunologie (Prof. Knolle)
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