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- Dokumenttyp:
- Journal Article; Research Support, Non-U.S. Gov't
- Autor(en):
- Takigawa, Masateru; Kitamura, Takeshi; Basu, Shubhayu; Bartal, Meir; Martin, Claire A; Martin, Ruairidh; Cheniti, Ghassen; Vlachos, Konstantinos; Pillois, Xavier; Frontera, Antonio; Massoullié, Grégoire; Thompson, Nathaniel; Bourier, Felix; Lam, Anna; Duchateau, Josselin; Pambrun, Thomas; Denis, Arnaud; Derval, Nicolas; Cochet, Hubert; Haïssaguerre, Michel; Sacher, Frederic; Hocini, Mélèze; Jaïs, Pierre
- Titel:
- Effect of electrode size and spacing on electrograms: Optimized electrode configuration for near-field electrogram characterization.
- Abstract:
- BACKGROUND: Detailed effects of electrode size on electrograms (EGMs) have not been systematically examined. OBJECTIVES: We aimed to elucidate the effect of electrode size on EGMs and investigate an optimal configuration of electrode size and interelectrode spacing for gap detection and far-field reduction. METHODS: This study included 8 sheep in which probes with different electrode size and interelectrode spacing were epicardially placed on healthy, fatty, and lesion tissues for measurements. Between 3 electrode sizes (0.1 mm/0.2 mm/0.5 mm) with 3 mm spacing. As indices of capability in gap detection and far-field reduction, in different electrode sizes (0.1 mm/0.2 mm/0.5 mm) and interelectrode spacing (0.1 mm/0.2 mm/0.3 mm/0.5 mm/3 mm) and the optimized electrode size and interelectrode spacing were determined. Compared between PentaRay and the optimal probe determined in study 2. RESULTS: Study 1 demonstrated that unipolar voltage and the duration of EGMs increased as the electrode size increased in any tissue (P < .001). Bipolar EGMs had the same tendency in healthy/fat tissues, but not in lesions. Study 2 showed that significantly higher gap to lesion volume ratio and healthy to fat tissue voltage ratio were provided by a smaller electrode (0.2 mm or 0.3 mm electrode) and smaller spacing (0.1 mm spacing), but 0.3 mm electrode/0.1 mm spacing provided a larger bipolar voltage (P < .05). Study 3 demonstrated that 0.3 mm electrode/0.1 mm spacing provided less deflection with more discrete EGMs (P < .0001) with longer and more reproducible AF cycle length (P < .0001) compared to PentaRay. CONCLUSION: Electrode size affects both unipolar and bipolar EGMs. Catheters with microelectrodes and very small interelectrode spacing may be superior in gap detection and far-field reduction. Importantly, this electrode configuration could dramatically reduce artifactual complex fractionated atrial electrograms and may open a new era for AF mapping.
- Zeitschriftentitel:
- Heart Rhythm
- Jahr:
- 2022
- Band / Volume:
- 19
- Heft / Issue:
- 1
- Seitenangaben Beitrag:
- 102-112
- Volltext / DOI:
- doi:10.1016/j.hrthm.2021.09.011
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/34534699
- Print-ISSN:
- 1547-5271
- TUM Einrichtung:
- Klinik für Herz- und Kreislauferkrankungen im Erwachsenenalter (Prof. Schunkert)
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