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Dokumenttyp:
Zeitschriftenaufsatz
Autor(en):
G. Fiorito; S. Pedron; C. Ochoa-Rosales; C. McCrory; S. Polidoro; Y. Zhang; P.-A. Dugué; S. Ratliff; W. N. Zhao; G. J. McKay; G. Costa; M. G. Solinas; K. M. Harris; R. Tumino; S. Grioni; F. Ricceri; S. Panico; H. Brenner; L. Schwettmann; M. Waldenberger; P. R. Matias-Garcia; A. Peters; A. Hodge; G. G. Giles; L. L. Schmitz; M. Levine; J. A. Smith; Y. Liu; F. Kee; I. S. Young; B. McGuinness; A. J. McKnight; J. van Meurs; T. Voortman; R. A. Kenny; P. Vineis; C. C...    »
Titel:
The role of epigenetic clocks in explaining educational inequalities in mortality: a multi-cohort study and meta-analysis
Abstract:
Educational inequalities in all-cause mortality have been observed for decades. However, the underlying biological mechanisms are not well known. We aimed to assess the role of DNA methylation changes in blood captured by epigenetic clocks in explaining these inequalities. Data were from eight prospective population-based cohort studies, representing 13,021 participants. First, educational inequalities and their portion explained by Horvath DNAmAge, Hannum DNAmAge, DNAmPhenoAge, and DNAmGrimA...    »
Stichworte:
DNA methylation, biomarkers, longevity, social inequalities
Zeitschriftentitel:
The journals of gerontology. Series A, Biological sciences and medical sciences
Jahr:
2022
Band / Volume:
Series A, glac041
Jahr / Monat:
2022-02
Quartal:
1. Quartal
Monat:
Feb
Heft / Issue:
Series A, glac041
Reviewed:
ja
Sprache:
en
Volltext / DOI:
doi:10.1093/gerona/glac041
WWW:
https://academic.oup.com/biomedgerontology/advance-article-abstract/doi/10.1093/gerona/glac041/6529712
Verlag / Institution:
The journals of gerontology. Series A, Biological sciences and medical sciences
Impact Factor:
6,053
Scimago-Quartil:
Q1
Status:
Verlagsversion / published
Eingereicht (bei Zeitschrift):
15.05.2021
Publikationsdatum:
17.02.2022
Semester:
WS 21-22
Format:
Bild/Text
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