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- Dokumenttyp:
- Zeitschriftenaufsatz
- Autor(en):
- S. Würstle; J. Erber; M. Hanselmann; D. Hoffmann; S. Werfel; S. Hering; S. Weidlich; J. Schneider; R. Franke; M. Maier; A. G. Henkel; R. M. Schmid; U. Protzer; M. Laxy; C. D. Spinner
- Titel:
- A Telemedicine-Guided Self-Collection Approach for PCR-Based SARS-CoV-2 Testing: Comparative Study
- Abstract:
- Background: Large-scale, polymerase chain reaction (PCR)-based SARS-CoV-2 testing is expensive, resource intensive, and time consuming. A self-collection approach is a probable alternative; however, its feasibility, cost, and ability to prevent infections need to be evaluated. Objective: This study aims to compare an innovative self-collection approach with a regular SARS-CoV-2 testing strategy in a large European industrial manufacturing site. Methods: The feasibility of a telemedicine-guided PCR-based self-collection approach was assessed for 150 employees (intervention group) and compared with a regular SARS-CoV-2 testing approach used for 143 employees (control group). Acceptance, ergonomics, and efficacy were evaluated using a software application. A simulation model was implemented to evaluate the effectiveness. An interactive R shiny app was created to enable customized simulations. Results: The test results were successfully communicated to and interpreted without uncertainty by 76% (114/150) and 76.9% (110/143) of the participants in the intervention and control groups, respectively (P=.96). The ratings for acceptability, ergonomics, and efficacy among intervention group participants were noninferior when compared to those among control group participants (acceptability: 71.6% vs 37.6%; ergonomics: 88.1% vs 74.5%; efficacy: 86.4% vs 77.5%). The self-collection approach was found to be less time consuming (23 min vs 38 min; P<.001). The simulation model indicated that both testing approaches reduce the risk of infection, and the self-collection approach tends to be slightly less effective owing to its lower sensitivity. Conclusions: The self-collection approach for SARS-CoV-2 diagnosis was found to be technically feasible and well rated in terms of acceptance, ergonomics, and efficacy. The simulation model facilitates the evaluation of test effectiveness; nonetheless, considering context specificity, appropriate adaptation by companies is required. JMIR Form Res 2022; 6(1):e32564
- Stichworte:
- self-sampling (2); telemedicine (308); test strategy effectiveness; simulation model; SARS-CoV-2 (144); COVID-19 (922)
- Zeitschriftentitel:
- JMIR Formative Research
- Jahr:
- 2022
- Band / Volume:
- JMIR Form Res 2022; 6(1):e32564
- Jahr / Monat:
- 2022-01
- Quartal:
- 1. Quartal
- Monat:
- Jan
- Reviewed:
- ja
- Sprache:
- en
- Volltext / DOI:
- doi:10.2196/32564
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/34803022
- WWW:
- https://formative.jmir.org/2022/1/e32564/
- Verlag / Institution:
- JMIR Formative Research
- Impact Factor:
- 5,428
- Scimago-Quartil:
- Q1
- Status:
- Verlagsversion / published
- Eingereicht (bei Zeitschrift):
- 02.08.2021
- Angenommen (von Zeitschrift):
- 21.11.2021
- Publikationsdatum:
- 04.01.2022
- Semester:
- WS 21-22
- Format:
- Bild/Text
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