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Document type:
Article; Journal Article; Review 
Author(s):
Jost, Philipp J; Vucic, Domagoj 
Title:
Regulation of Cell Death and Immunity by XIAP. 
Abstract:
X-chromosome-linked inhibitor of apoptosis protein (XIAP) controls cell survival in several regulated cell death pathways and coordinates a range of inflammatory signaling events. Initially identified as a caspase-binding protein, it was considered to be primarily involved in blocking apoptosis from both intrinsic as well as extrinsic triggers. However, XIAP also prevents TNF-mediated, receptor-interacting protein 3 (RIPK3)-dependent cell death, by controlling RIPK1 ubiquitylation and preventing...    »
 
Journal title abbreviation:
Cold Spring Harb Perspect Biol 
Year:
2020 
Journal volume:
12 
Journal issue:
Print-ISSN:
1943-0264 
TUM Institution:
III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie)