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Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Singh, AP; Shah, PP; Mathur, N; Buters, JT; Pant, MC; Parmar, D
Titel:
Genetic polymorphisms in cytochrome P4501B1 and susceptibility to head and neck cancer.
Abstract:
Cytochrome P4501B1 (CYP1B1), a polycyclic aromatic hydrocarbon (PAH) metabolizing CYP, is genetically polymorphic in humans and may be involved in the individual susceptibility to chemical-induced cancer. In the present study, genotype and haplotype frequencies of four single nucleotide polymorphisms (SNPs) in CYP1B1 that cause amino acid changes (Arg-Gly at codon 48, Ala-Ser at codon 119, Leu-Val at codon 432 and Asn-Ser at codon 453) were studied in 150 cases suffering from head and neck squam...    »
Zeitschriftentitel:
Mutat Res
Jahr:
2008
Band / Volume:
639
Heft / Issue:
1-2
Seitenangaben Beitrag:
11-9
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.mrfmmm.2007.10.007
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18067928
Print-ISSN:
0027-5107
TUM Einrichtung:
Molekulare Allergologie (Prof. Schmidt-Weber)
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