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Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't 
Autor(en):
Mannell, H; Pircher, J; Fochler, F; Stampnik, Y; Räthel, T; Gleich, B; Plank, C; Mykhaylyk, O; Dahmani, C; Wörnle, M; Ribeiro, A; Pohl, U; Krötz, F 
Titel:
Site directed vascular gene delivery in vivo by ultrasonic destruction of magnetic nanoparticle coated microbubbles. 
Abstract:
Site specific vascular gene delivery for therapeutic implications is favorable because of reduction of possible side effects. Yet this technology faces numerous hurdles that result in low transfection rates because of suboptimal delivery. Combining ultrasonic microbubble technology with magnetic nanoparticle enhanced gene transfer could make it possible to use the systemic vasculature as the route of application and to magnetically trap these compounds at the target of interest. In this study we...    »
 
Zeitschriftentitel:
Nanomedicine 
Jahr:
2012 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
1309-18 
Sprache:
eng 
Print-ISSN:
1549-9634 
TUM Einrichtung:
Institut für Experimentelle Onkologie und Therapieforschung 
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