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Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't 
Autor(en):
Banci, Lucia; Ciofi-Baffoni, Simone; Gajda, Karolina; Muzzioli, Riccardo; Peruzzini, Riccardo; Winkelmann, Julia 
Titel:
N-terminal domains mediate [2Fe-2S] cluster transfer from glutaredoxin-3 to anamorsin. 
Abstract:
In eukaryotes, cytosolic monothiol glutaredoxins are proteins implicated in intracellular iron trafficking and sensing via their bound [2Fe-2S] clusters. We define a new role of human cytosolic monothiol glutaredoxin-3 (GRX3) in transferring its [2Fe-2S] clusters to human anamorsin, a physical and functional protein partner of GRX3 in the cytosol, whose [2Fe-2S] cluster-bound form is involved in the biogenesis of cytosolic and nuclear Fe-S proteins. Specific protein recognition between the N-ter...    »
 
Zeitschriftentitel:
Nat Chem Biol 
Jahr:
2015 
Band / Volume:
11 
Heft / Issue:
10 
Seitenangaben Beitrag:
772-8 
Sprache:
eng 
Volltext / DOI:
Print-ISSN:
1552-4450 
TUM Einrichtung:
Institut für Humangenetik