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Document type:
Zeitschriftenaufsatz
Author(s):
Cattani-Scholz, A.; Pedone, D.; Dubey, M.; Neppl, S.; Nickel, B.; Feulner, P.; Schwartz, J.; Abstreiter, G.; Tornow, M.
Title:
Organophosphonate based PNA-functionalization of silicon nanowires for label-free DNA detection
Abstract:
We investigated hydroxyalkylphosphonate monolayers as a novel platform for the biofunctionalization of silicon-based field effect sensor devices. This included a detailed study of the thin film properties of organophosphonate films on Si substrates using several surface analysis techniques, including AFM, ellipsometry, contact angle, X-ray photoelectron spectroscopy (XPS), X-ray reflectivity, and current-voltage characteristics in electrolyte solution. Our results indicate the formation of a den...     »
Keywords:
biosensor · DNA/PNA hybridization · surface characterization · XPS · X-ray reflectivity · organophosphonate monolayers · heterobifunctional linker · silicon nanowire device
Journal title:
ACS Nano Org, VOL. 2 ▪ NO. 8 ▪ 1653–1660 ▪ 2008
Year:
2008
Year / month:
2008-07
Quarter:
3. Quartal
Month:
Jul
Pages contribution:
1653-1660
Fulltext / DOI:
doi:10.1021/nn800136e
WWW:
http://www.researchgate.net/publication/23997045_Organophosphonate-Based_PNA-Functionalization_of_Silicon_Nanowires_for_Label-Free_DNA_Detection
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