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Document type:
Zeitschriftenaufsatz 
Author(s):
Shahryary, Yadollah; Symeonidi, Aikaterini; Hazarika, Rashmi R.; Denkena, Johanna; Mubeen, Talha; Hofmeister, Brigitte; van Gurp, Thomas; Colomé-Tatché, Maria; Verhoeven, Koen; Tuskan, Gerald; Schmitz, Robert J; Johannes, Frank 
Title:
AlphaBeta: Computational inference of epimutation rates and spectra from high-throughput DNA methylation data in plants 
Abstract:
Introduction Heritable changes in cytosine methylation can arise stochastically in plant genomes independently of DNA sequence alterations. These so-called \textquoteleftspontaneous epimutations\textquoteright appear to be a byproduct of imperfect DNA methylation maintenance during mitotic or meitotic cell divisions. Accurate estimates of the rate and spectrum of these stochastic events are necessary to be able to quantify how epimutational processes shape methylome diversity in the context of p...    »
 
Journal title:
bioRxiv 
Year:
2020 
Fulltext / DOI:
Publisher:
Cold Spring Harbor Laboratory