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Document type:
journal article 
Author(s):
Fard, Maryam K; van der Meer, Franziska; Sánchez, Paula; Cantuti-Castelvetri, Ludovico; Mandad, Sunit; Jäkel, Sarah; Fornasiero, Eugenio F; Schmitt, Sebastian; Ehrlich, Marc; Starost, Laura; Kuhlmann, Tanja; Sergiou, Christina; Schultz, Verena; Wrzos, Claudia; Brück, Wolfgang; Urlaub, Henning; Dimou, Leda; Stadelmann, Christine; Simons, Mikael 
Title:
BCAS1 expression defines a population of early myelinating oligodendrocytes in multiple sclerosis lesions. 
Abstract:
Investigations into brain function and disease depend on the precise classification of neural cell types. Cells of the oligodendrocyte lineage differ greatly in their morphology, but accurate identification has thus far only been possible for oligodendrocyte progenitor cells and mature oligodendrocytes in humans. We find that breast carcinoma amplified sequence 1 (BCAS1) expression identifies an oligodendroglial subpopulation in the mouse and human brain. These cells are newly formed, myelinatin...    »
 
Journal title abbreviation:
Sci Transl Med 
Year:
2017 
Journal volume:
Journal issue:
419 
Language:
eng 
Print-ISSN:
1946-6234 
TUM Institution:
Institut für Zellbiologie des Nervensystems