In this study we show, using flow cytometry and angiography, that in patients with acute myocardial infarction the influence of erythropoietin leads to a higher concentration of circulating CD133+ progenitor cells but not to a higher expression of CXCR4 on this cell fraction. Moreover, erythropoietin increases in angiography the development of restenosis, whereas this event neither correlates with the concentration of circulating progenitor cells nor with the expression of CXCR4. However, the frequency of major adverse cardiovascular or cerebral events correlates in trend with the concentration of circulating CD133+ progenitor cells.
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In this study we show, using flow cytometry and angiography, that in patients with acute myocardial infarction the influence of erythropoietin leads to a higher concentration of circulating CD133+ progenitor cells but not to a higher expression of CXCR4 on this cell fraction. Moreover, erythropoietin increases in angiography the development of restenosis, whereas this event neither correlates with the concentration of circulating progenitor cells nor with the expression of CXCR4. However, the fr...
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