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Document type:
Journal Article; Review 
Author(s):
Gillen, S; Schuster, T; Meyer Zum Büschenfelde, C; Friess, H; Kleeff, J 
Title:
Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentages. 
Abstract:
BACKGROUND: Pancreatic cancer has an extremely poor prognosis and prolonged survival is achieved only by resection with macroscopic tumor clearance. There is a strong rationale for a neoadjuvant approach, since a relevant percentage of pancreatic cancer patients present with non-metastatic but locally advanced disease and microscopic incomplete resections are common. The objective of the present analysis was to systematically review studies concerning the effects of neoadjuvant therapy on tumor...    »
 
Journal title abbreviation:
PLoS Med 
Year:
2010 
Journal volume:
Journal issue:
Pages contribution:
e1000267 
Language:
eng 
Print-ISSN:
1549-1277 
TUM Institution:
Chirurgische Klinik und Poliklinik; III. Medizinische Klinik und Poliklinik (Hämatologie / Onkologie); Institut für Medizinische Statistik und Epidemiologie