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Document type:
Journal Article; Journal Article
Author(s):
Du, Yang; Jiang, Qiao; Beziere, Nicolas; Song, Linlin; Zhang, Qian; Peng, Dong; Chi, Chongwei; Yang, Xin; Guo, Hongbo; Diot, Gael; Ntziachristos, Vasilis; Ding, Baoquan; Tian, Jie
Title:
DNA-Nanostructure-Gold-Nanorod Hybrids for Enhanced In Vivo Optoacoustic Imaging and Photothermal Therapy.
Abstract:
A functional cancer theranostic nanoplatform is developed, specifically tailored toward the optoacoustic modality by combining gold nanorods with DNA nanostructures (D-AuNR). DNA origami is used as an efficient delivery vehicle owing to its prominent tumor-targeting property. The D-AuNR hybrids display an enhanced tumor diagnostic sensitivity by improved optoacoustic imaging and excellent photothermal therapeutic properties in vivo.
Journal title abbreviation:
Adv Mater Deerfield
Year:
2016
Journal volume:
28
Journal issue:
45
Pages contribution:
10000-10007
Language:
eng
Fulltext / DOI:
doi:10.1002/adma.201601710
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/27679425
Print-ISSN:
0935-9648
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)
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