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Document type:
journal article 
Author(s):
Tzoumas, Stratis; Nunes, Antonio; Olefir, Ivan; Stangl, Stefan; Symvoulidis, Panagiotis; Glasl, Sarah; Bayer, Christine; Multhoff, Gabriele; Ntziachristos, Vasilis 
Title:
Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues. 
Abstract:
Light propagating in tissue attains a spectrum that varies with location due to wavelength-dependent fluence attenuation, an effect that causes spectral corruption. Spectral corruption has limited the quantification accuracy of optical and optoacoustic spectroscopic methods, and impeded the goal of imaging blood oxygen saturation (sO2) deep in tissues; a critical goal for the assessment of oxygenation in physiological processes and disease. Here we describe light fluence in the spectral domain...    »
 
Journal title abbreviation:
Nat Commun 
Year:
2016 
Journal volume:
Pages contribution:
12121 
Language:
eng 
Fulltext / DOI:
TUM Institution:
Lehrstuhl für Biologische Bildgebung; Klinik und Poliklinik für RadioOnkologie und Strahlentherapie