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Document type:
journal article 
Author(s):
Gehrmann, Mathias K; Kimm, Melanie A; Stangl, Stefan; Schmid, Thomas E; Noël, Peter B; Rummeny, Ernst J; Multhoff, Gabriele 
Title:
Imaging of Hsp70-positive tumors with cmHsp70.1 antibody-conjugated gold nanoparticles. 
Abstract:
Real-time imaging of small tumors is still one of the challenges in cancer diagnosis, prognosis, and monitoring of clinical outcome. Targeting novel biomarkers that are selectively expressed on a large variety of different tumors but not normal cells has the potential to improve the imaging capacity of existing methods such as computed tomography. Herein, we present a novel technique using cmHsp70.1 monoclonal antibody-conjugated spherical gold nanoparticles for quantification of the targeted up...    »
 
Journal title abbreviation:
Int J Nanomedicine 
Year:
2015 
Journal volume:
10 
Pages contribution:
5687-700 
Language:
eng 
Print-ISSN:
1176-9114 
TUM Institution:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie; Institut für Radiologie