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Document type:
journal article 
Author(s):
Thibaudeau, Laure; Taubenberger, Anna V; Theodoropoulos, Christina; Holzapfel, Boris M; Ramuz, Olivier; Straub, Melanie; Hutmacher, Dietmar W 
Title:
New mechanistic insights of integrin ?1 in breast cancer bone colonization. 
Abstract:
Bone metastasis is a frequent and life-threatening complication of breast cancer. The molecular mechanisms supporting the establishment of breast cancer cells in the skeleton are still not fully understood, which may be attributed to the lack of suitable models that interrogate interactions between human breast cancer cells and the bone microenvironment. Although it is well-known that integrins mediate adhesion of malignant cells to bone extracellular matrix, their role during bone colonization...    »
 
Journal title abbreviation:
Oncotarget 
Year:
2015 
Journal volume:
Journal issue:
Pages contribution:
332-44 
Language:
eng 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie