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Document type:
Zeitschriftenaufsatz 
Author(s):
Arends, Fabienna; Sellner, Sabine; Seifert, Philipp; Gerland, Ulrich; Rehberg, Markus; Lieleg, Oliver 
Title:
A microfluidics approach to study the accumulation of molecules at basal lamina interfaces 
Abstract:
For an efficient distribution of drugs and drug carriers through biological barriers such as the vascular system, the size and surface properties of nanoparticles and molecules play a key role. To screen for important parameters which determine the ability of drugs or drug carriers to translocate through complex biological barriers, an in vitro assay which correctly predicts the behavior of those objects in vivo would be highly desirable. Here, we present a microfluidic setup to probe the diffus...    »
 
Keywords:
drug carrier, basal lamina, vascular system, biological barrier 
Dewey Decimal Classification:
500 Naturwissenschaften 
Journal title:
Lab Chip 
Year:
2015 
Journal volume:
15 
Journal issue:
16 
Pages contribution:
3326-3334 
Covered by:
Web of Science 
Reviewed:
ja 
Language:
en 
Fulltext / DOI:
Publisher:
Royal Society of Chemistry (RSC) 
Publisher address:
England 
Print-ISSN:
1473-0189 
Date of publication:
01.01.2015 
TUM Institution:
Fachgebiet für Biomechanik 
Ingested:
12.08.2015