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Document type:
journal article 
Author(s):
Beer, Ambros J; Pelisek, Jaroslav; Heider, Peter; Saraste, Antti; Reeps, Christian; Metz, Stephan; Seidl, Stefan; Kessler, Horst; Wester, Hans-Jürgen; Eckstein, Hans Henning; Schwaiger, Markus 
Title:
PET/CT imaging of integrin ?v?3 expression in human carotid atherosclerosis. 
Abstract:
The goal of this study was to evaluate the feasibility of [(18)F]Galacto-RGD positron emission tomography (PET)/computed tomography (CT) imaging of ?v?3 expression in human carotid plaques.The integrin ?v?3 is expressed by macrophages and angiogenic endothelial cells in atherosclerotic lesions and thus is a marker of plaque inflammation and, potentially, of plaque vulnerability. [(18)F]Galacto-RGD is a PET tracer binding specifically to ?v?3. Therefore, [(18)F]Galacto-RGD PET/CT imaging of ?v?3...    »
 
Journal title abbreviation:
JACC Cardiovasc Imaging 
Year:
2014 
Journal volume:
Journal issue:
Pages contribution:
178-87 
Language:
eng 
Print-ISSN:
1936-878X 
TUM Institution:
Nuklearmedizinische Klinik und Poliklinik; Klinik für Gefäßchirurgie; Institut für Radiologie