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Dokumenttyp:
journal article 
Autor(en):
Org, E; Eyheramendy, S; Juhanson, P; Gieger, C; Lichtner, P; Klopp, N; Veldre, G; Döring, A; Viigimaa, M; Sõber, S; Tomberg, K; Eckstein, G; KORA; Kelgo, P; Rebane, T; Shaw-Hawkins, S; Howard, P; Onipinla, A; Dobson, RJ; Newhouse, SJ; Brown, M; Dominiczak, A; Connell, J; Samani, N; Farrall, M; BRIGHT; Caulfield, MJ; Munroe, PB; Illig, T; Wichmann, HE; Meitinger, T; Laan, M 
Titel:
Genome-wide scan identifies CDH13 as a novel susceptibility locus contributing to blood pressure determination in two European populations. 
Abstract:
Hypertension is a complex disease that affects a large proportion of adult population. Although approximately half of the inter-individual variance in blood pressure (BP) level is heritable, identification of genes responsible for its regulation has remained challenging. Genome-wide association study (GWAS) is a novel approach to search for genetic variants contributing to complex diseases. We conducted GWAS for three BP traits [systolic and diastolic blood pressure (SBP and DBP); hypertension...    »
 
Zeitschriftentitel:
Hum Mol Genet 
Jahr:
2009 
Band / Volume:
18 
Heft / Issue:
12 
Seitenangaben Beitrag:
2288-96 
Sprache:
eng 
Print-ISSN:
0964-6906 
TUM Einrichtung:
r Humangenetik