User: Guest  Login
Document type:
journal article 
Author(s):
Gluz, O; Mengele, K; Schmitt, M; Kates, R; Diallo-Danebrock, R; Neff, F; Royer, HD; Eckstein, N; Mohrmann, S; Ting, E; Kiechle, M; Poremba, C; Nitz, U; Harbeck, N 
Title:
Y-box-binding protein YB-1 identifies high-risk patients with primary breast cancer benefiting from rapidly cycled tandem high-dose adjuvant chemotherapy. 
Abstract:
PURPOSE: To investigate the potential of Y-box-binding protein YB-1, a multifunctional protein linked to tumor aggressiveness and multidrug resistance, to identify patients with breast cancer likely to benefit from dose-intensified chemotherapy regimens. PATIENTS AND METHODS: YB-1 was immunohistochemically determined in 211 primary tumors from the prospective, randomized West German Study Group WSG-AM-01 trial in high-risk (> or = 10 involved lymph-nodes) breast cancer (HRBC). Predictive impact...    »
 
Journal title abbreviation:
J Clin Oncol 
Year:
2009 
Journal volume:
27 
Journal issue:
36 
Pages contribution:
6144-51 
Language:
eng 
Print-ISSN:
0732-183X 
TUM Institution:
Frauenklinik und Poliklinik