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Dokumenttyp:
journal article 
Autor(en):
Hoermannsperger, G; Hörmannsperger, G; Clavel, T; Hoffmann, M; Reiff, C; Kelly, D; Loh, G; Blaut, M; Hölzlwimmer, G; Laschinger, M; Haller, D 
Titel:
Post-translational inhibition of IP-10 secretion in IEC by probiotic bacteria: impact on chronic inflammation. 
Abstract:
BACKGROUND: Clinical and experimental studies suggest that the probiotic mixture VSL#3 has protective activities in the context of inflammatory bowel disease (IBD). The aim of the study was to reveal bacterial strain-specific molecular mechanisms underlying the anti-inflammatory potential of VSL#3 in intestinal epithelial cells (IEC). METHODOLOGY/PRINCIPAL FINDINGS: VSL#3 inhibited TNF-induced secretion of the T-cell chemokine interferon-inducible protein (IP-10) in Mode-K cells. Lactobacillus c...    »
 
Zeitschriftentitel:
PLoS ONE 
Jahr:
2009 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
e4365 
Sprache:
eng 
TUM Einrichtung:
Chirurgiesche Klinik und Poliklinik