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Dokumenttyp:
journal article 
Autor(en):
Waaga-Gasser, AM; Grimm, MR; Lutz, J; Lange, V; Lenhard, SM; Aviles, B; Kist-van Holthe, JE; Lebedeva, T; Samsonov, D; Meyer, D; Hancock, WW; Heemann, U; Gasser, M; Chandraker, A 
Titel:
Regulatory allospecific T cell clones abrogate chronic allograft rejection. 
Abstract:
True alloantigen-specific tolerance is the ultimate goal of solid organ transplantation, eliminating the need for long-term immunosuppression. Recent evidence suggests that Th1-derived cytokines are associated with rejection and Th2-derived cytokines with long-term allograft survival, but the roles of these subsets in rejection and tolerance are incompletely understood. Here, we analyzed the functional and regulatory capacities of T cell clones derived from tolerant and rejecting rats (Wistar ra...    »
 
Zeitschriftentitel:
J Am Soc Nephrol 
Jahr:
2009 
Band / Volume:
20 
Heft / Issue:
Seitenangaben Beitrag:
820-30 
Sprache:
eng 
Print-ISSN:
1046-6673 
TUM Einrichtung:
r Nephrologie