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Document type:
journal article 
Author(s):
Buhl, A; Page, S; Heegaard, NH; von Landenberg, P; Luppa, PB 
Title:
Optical biosensor-based characterization of anti-double-stranded DNA monoclonal antibodies as possible new standards for laboratory tests. 
Abstract:
The serum determination of circulating anti-double-stranded (ds)DNA autoantibodies is a routine measure for the laboratory diagnosis of systemic lupus erythematosus. Since available assays differ substantially and no feasible calibrator is available, the aim of this study was to evaluate a recently introduced surface plasmon resonance (SPR) biosensor chip for binding studies between dsDNA and anti-dsDNA autoantibodies and to demonstrate its usefulness for the characterization of new monoclonal a...    »
 
Journal title abbreviation:
Biosens Bioelectron 
Year:
2009 
Journal volume:
25 
Journal issue:
Pages contribution:
198-203 
Language:
eng 
Print-ISSN:
0956-5663 
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie