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Dokumenttyp:
journal article 
Autor(en):
Ng, EK; Tsang, WP; Ng, SS; Jin, HC; Yu, J; Li, JJ; Röcken, C; Ebert, MP; Kwok, TT; Sung, JJ 
Titel:
MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. 
Abstract:
BACKGROUND: MicroRNAs (miRNAs) are 19-25-nucleotides regulatory non-protein-coding RNA molecules that regulate the expressions of a wide variety of genes, including some involved in cancer development. In this study, we investigated the possible role of miR-143 in colorectal cancer (CRC). METHODS: Expression levels of human mature miRNAs were examined using real-time PCR-based expression arrays on paired colorectal carcinomas and adjacent non-cancerous colonic tissues. The downregulation of miR-...    »
 
Zeitschriftentitel:
Br J Cancer 
Jahr:
2009 
Band / Volume:
101 
Heft / Issue:
Seitenangaben Beitrag:
699-706 
Sprache:
eng 
Print-ISSN:
0007-0920 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik