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Dokumenttyp:
journal article 
Autor(en):
Ahmed, S; Thomas, G; Ghoussaini, M; Healey, CS; Humphreys, MK; Platte, R; Morrison, J; Maranian, M; Pooley, KA; Luben, R; Eccles, D; Evans, DG; Fletcher, O; Johnson, N; dos Santos Silva, I; Peto, J; Stratton, MR; Rahman, N; Jacobs, K; Prentice, R; Anderson, GL; Rajkovic, A; Curb, JD; Ziegler, RG; Berg, CD; Buys, SS; McCarty, CA; Feigelson, HS; Calle, EE; Thun, MJ; Diver, WR; Bojesen, S; Nordestgaard, BG; Flyger, H; Dörk, T; Schürmann, P; Hillemanns, P; Karstens, JH; Bogdanova, NV; Antonenkova, N...    »
 
Titel:
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2. 
Abstract:
Genome-wide association studies (GWAS) have identified seven breast cancer susceptibility loci, but these explain only a small fraction of the familial risk of the disease. Five of these loci were identified through a two-stage GWAS involving 390 familial cases and 364 controls in the first stage, and 3,990 cases and 3,916 controls in the second stage. To identify additional loci, we tested over 800 promising associations from this GWAS in a further two stages involving 37,012 cases and 40,069 c...    »
 
Zeitschriftentitel:
Nat Genet 
Jahr:
2009 
Band / Volume:
41 
Heft / Issue:
Seitenangaben Beitrag:
585-90 
Sprache:
eng 
Print-ISSN:
1061-4036 
TUM Einrichtung:
Frauenklinik und Poliklinik