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Document type:
journal article 
Author(s):
Hartmaier, RJ; Tchatchou, S; Richter, AS; Wang, J; McGuire, SE; Skaar, TC; Rae, JM; Hemminki, K; Sutter, C; Ditsch, N; Bugert, P; Weber, BH; Niederacher, D; Arnold, N; Varon-Mateeva, R; Wappenschmidt, B; Schmutzler, RK; Meindl, A; Bartram, CR; Burwinkel, B; Oesterreich, S 
Title:
Nuclear receptor coregulator SNP discovery and impact on breast cancer risk. 
Abstract:
BACKGROUND: Coregulator proteins are "master regulators", directing transcriptional and posttranscriptional regulation of many target genes, and are critical in many normal physiological processes, but also in hormone driven diseases, such as breast cancer. Little is known on how genetic changes in these genes impact disease development and progression. Thus, we set out to identify novel single nucleotide polymorphisms (SNPs) within SRC-1 (NCoA1), SRC-3 (NCoA3, AIB1), NCoR (NCoR1), and SMRT (NCo...    »
 
Journal title abbreviation:
BMC Cancer 
Year:
2009 
Journal volume:
Pages contribution:
438 
Language:
eng 
TUM Institution:
Frauenklinik und Poliklinik