Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Martens, JW; Margossian, AL; Schmitt, M; Foekens, J; Harbeck, N 
Titel:
DNA methylation as a biomarker in breast cancer. 
Abstract:
In cancer, epigenetic changes such as covalent addition of methyl groups to the genomic DNA itself are more prominent than genetic changes. Cytosine-phosphate-guanosine (CpG) methylation negatively affects gene transcription of an adjacent gene. It is thought that DNA methylation significantly contributes to all hallmarks of cancer. Next to being a potential therapy target, DNA methylation is an emerging field of biomarkers. Technically, DNA provides a stable and robust analyte that is particula...    »
 
Zeitschriftentitel:
Future Oncol 
Jahr:
2009 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
1245-56 
Sprache:
eng 
Print-ISSN:
1479-6694 
TUM Einrichtung:
Frauenklinik und Poliklinik