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Dokumenttyp:
journal article 
Autor(en):
Graeser, MK; Engel, C; Rhiem, K; Gadzicki, D; Bick, U; Kast, K; Froster, UG; Schlehe, B; Bechtold, A; Arnold, N; Preisler-Adams, S; Nestle-Kraemling, C; Zaino, M; Loeffler, M; Kiechle, M; Meindl, A; Varga, D; Schmutzler, RK 
Titel:
Contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers. 
Abstract:
PURPOSE: To estimate the risk for contralateral breast cancer in members of BRCA1- and BRCA2-positive families and to determine predictive risk factors. PATIENTS AND METHODS: A retrospective, multicenter, cohort study was performed from 1996 until 2008 and comprised 2,020 women with unilateral breast cancer (index patients, n = 978; relatives, n = 1.42) from 978 families who had a BRCA1 or BRCA2 mutation. Cox regression analysis was applied to assess the association of age at first breast cance...    »
 
Zeitschriftentitel:
J Clin Oncol 
Jahr:
2009 
Band / Volume:
27 
Heft / Issue:
35 
Seitenangaben Beitrag:
5887-92 
Sprache:
eng 
Print-ISSN:
0732-183X 
TUM Einrichtung:
Frauenklinik und Poliklinik