Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Brilot, F; Dale, RC; Selter, RC; Grummel, V; Kalluri, SR; Aslam, M; Busch, V; Zhou, D; Cepok, S; Hemmer, B 
Titel:
Antibodies to native myelin oligodendrocyte glycoprotein in children with inflammatory demyelinating central nervous system disease. 
Abstract:
OBJECTIVE: Myelin oligodendrocyte glycoprotein (MOG) is a candidate target antigen in demyelinating diseases of the central nervous system (CNS). Although MOG is encephalitogenic in different animal models, the relevance of this antigen in human autoimmune diseases of the CNS is still controversial. METHODS: We investigated the occurrence and biological activity of antibodies to native MOG (nMOG) in 47 children during a first episode of CNS demyelination (acute disseminated encephalomyelitis [AD...    »
 
Zeitschriftentitel:
Ann Neurol 
Jahr:
2009 
Band / Volume:
66 
Heft / Issue:
Seitenangaben Beitrag:
833-42 
Sprache:
eng 
Print-ISSN:
0364-5134 
TUM Einrichtung:
Neurologische Klinik und Poliklinik; Kinderklinik und Poliklinik