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Dokumenttyp:
journal article 
Autor(en):
Hamacher, R; Diersch, S; Scheibel, M; Eckel, F; Mayr, M; Rad, R; Bajbouj, M; Schmid, RM; Saur, D; Schneider, G 
Titel:
Interleukin 1 beta gene promoter SNPs are associated with risk of pancreatic cancer. 
Abstract:
Epidemiological and experimental data demonstrate, that inflammation contributes significantly to pancreatic carcinogenesis. IL1beta, a pleiotropic cytokine produced by inflammatory cells and tumor cells, promotes cancer progression. Single nucleotide polymorphisms (SNPs) of the IL1beta promoter were found to be associated with an increased risk for certain cancers. In this case-control study we determined IL1beta promoter SNPs in 73 patients with pancreatic cancer and 235 controls. We found tha...    »
 
Zeitschriftentitel:
Cytokine 
Jahr:
2009 
Band / Volume:
46 
Heft / Issue:
Seitenangaben Beitrag:
182-6 
Sprache:
eng 
Print-ISSN:
1043-4666 
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik