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Dokumenttyp:
journal article 
Autor(en):
Schröfelbauer, B; Raffetseder, J; Hauner, M; Wolkerstorfer, A; Ernst, W; Szolar, OH 
Titel:
Glycyrrhizin, the main active compound in liquorice, attenuates pro-inflammatory responses by interfering with membrane-dependent receptor signalling. 
Abstract:
The triterpene glycoside glycyrrhizin is the main active compound in liquorice. It is used as a herbal medicine owing to its anticancer, antiviral and anti-inflammatory properties. Its mode of action, however, remains widely unknown. In the present study, we aimed to elucidate the molecular mechanism of glycyrrhizin in attenuating inflammatory responses in macrophages. Using microarray analysis, we found that glycyrrhizin caused a broad block in the induction of pro-inflammatory mediators induce...    »
 
Zeitschriftentitel:
Biochem J 
Jahr:
2009 
Band / Volume:
421 
Heft / Issue:
Seitenangaben Beitrag:
473-82 
Sprache:
eng 
Print-ISSN:
0264-6021 
TUM Einrichtung:
hrungsmedizin