Translated abstract:
In this study, we investigated the influence of radiation on the expression and localisation of uPA, PAI-1 and VEGF in three xenografttumors of variable radiosensitivity by immunhistochemical staining and ELISA. The results of this study suggest that the expression (PAI-1, VEGF), as well as the localisation (uPA, PAI-1) of these proteins alter significantly during radiation. If these results are confirmed it may be possible to adjust radiation of the particular tumortype during treatment.