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Dokumenttyp:
journal article 
Autor(en):
Huster, KM; Stemberger, C; Gasteiger, G; Kastenmüller, W; Drexler, I; Busch, DH 
Titel:
Cutting edge: memory CD8 T cell compartment grows in size with immunological experience but nevertheless can lose function. 
Abstract:
The size of the adaptive immune system is considered to be kept constant by the attrition of pre-existing memory. However, recently it was shown that the CD8 memory compartment can grow in size and the number of pre-existing memory is largely preserved, predicting that pre-existing immunity should be maintained (Vezys et al.; Nature 457: 196-199). Experimental proof for this assumption is still lacking. We address this question in the Listeria monocytogenes (L.m.) infection model and confirm th...    »
 
Zeitschriftentitel:
J Immunol 
Jahr:
2009 
Band / Volume:
183 
Heft / Issue:
11 
Seitenangaben Beitrag:
6898-902 
Sprache:
eng 
Print-ISSN:
0022-1767 
TUM Einrichtung:
r Medizinische Mikrobiologie, Immunologie und Hygiene; r Virologie