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Document type:
journal article 
Author(s):
Levin, A; Hayouka, Z; Helfer, M; Brack-Werner, R; Friedler, A; Loyter, A 
Title:
Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration. 
Abstract:
BACKGROUND: The human immunodeficiency virus type 1 (HIV-1) integrase protein (IN), catalyzes the integration of viral DNA into the host cell genome. IN catalyzes the first step of the integration process, namely the 3'-end processing in which IN removes a pGT dinucleotide from the 3' end of each viral long terminal repeat (LTR). Following nuclear import of the viral preintegration complex, the host chromosomal DNA becomes accessible to the viral cDNA and the second step of the integration proce...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2009 
Journal volume:
Journal issue:
Pages contribution:
e4155 
Language:
eng 
TUM Institution:
Institut für Virologie