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Dokumenttyp:
journal article 
Autor(en):
Grimmer, T; Riemenschneider, M; Förstl, H; Henriksen, G; Klunk, WE; Mathis, CA; Shiga, T; Wester, HJ; Kurz, A; Drzezga, A 
Titel:
Beta amyloid in Alzheimer's disease: increased deposition in brain is reflected in reduced concentration in cerebrospinal fluid. 
Abstract:
BACKGROUND: A decreased concentration of beta amyloid (1-42) (Abeta42) has consistently been found in the cerebrospinal fluid (CSF) of patients with Alzheimer's disease (AD) and is considered a diagnostic biomarker. However, it is not clear to which extent CSF Abeta42 levels are reflective of cerebral pathology in AD. The aim of the study was to determine the association between cerebral amyloid plaque load, as measured by means of the positron emission tomography (PET) tracer carbon-11-labeled...    »
 
Zeitschriftentitel:
Biol Psychiatry 
Jahr:
2009 
Band / Volume:
65 
Heft / Issue:
11 
Seitenangaben Beitrag:
927-34 
Sprache:
eng 
Print-ISSN:
0006-3223 
TUM Einrichtung:
r Psychiatrie und Psychotherapie; Nuklearmedizinische Klinik und Poliklinik